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Stromal fragments meaning6/24/2023 Optimizing the multimodal approach to pancreatic cyst fluid diagnosis developing a volume-based triage protocol. Next-generation sequencing adds value to the preoperative diagnosis of pancreatic cysts. Precursor lesions in pancreatic cancer: morphological and molecular pathology. Scarlett CJ, Salisbury EL, Biankin AV, Kench J. A superior method for cell block preparation for fine-needle aspiration biopsies. Pancreatic cyst fluid triage: a critical component of the preoperative evaluation of pancreatic cysts. A meta-analysis of endoscopic ultrasound – fine-needle aspiration compared to endoscopic ultrasound – fine-needle biopsy: diagnostic yield and the value of onsite cytopathological assessment Authors. The presence of a cytopathologist increases the diagnostic accuracy of endoscopic ultrasound-guided fine needle aspiration cytology for pancreatic adenocarcinoma: a meta-analysis. Hébert-Magee S, Bae S, Varadarajulu S, et al. EUS-guided FNA for diagnosis of pancreatic cystic lesions: a meta-analysis. Endoscopic ultrasonography with fine-needle aspiration for histological diagnosis of solid pancreatic masses: a meta-analysis of diagnostic accuracy studies. 2017 6:S81.īanafea O, Mghanga FP, Zhao J, et al. Moray™ micro-forceps biopsy improves the diagnosis of specific pancreatic cysts. Zhang M, Arpin R, Brugge W, Forcione D, Omer Basar MP. Use of a novel through-the-needle biopsy forceps in endoscopic ultrasound. Shakhatreh MH, Naini SR, Brijbassie AA, et al. Novel fork-tip needles versus standard needles for EUS-guided tissue acquisition from solid masses of the upper GI tract: a matched cohort study. Endoscopic ultrasound-guided FNA and ProCore biopsy in sampling pancreatic and intra-abdominal masses. A meta-analysis comparing ProCore and standard fine-needle aspiration needles for endoscopic ultrasound-guided tissue acquisition. Endoscopic ultrasound-guided sampling of solid pancreatic masses: 22-gauge aspiration versus 25-gauge biopsy needles. Randomized trial comparing the flexible 19G and 25G needles for endoscopic ultrasound-guided fine needle aspiration of solid pancreatic mass lesions. Needle size has only a limited effect on outcomes in EUS-guided fine needle aspiration: a systematic review and meta-analysis. Ultrasound-guided vs endoscopic ultrasound-guided fine-needle aspiration for pancreatic cancer diagnosis. Endoscopic ultrasound-guided fine needle aspiration versus percutaneous ultrasound-guided fine needle aspiration in diagnosis of focal pancreatic masses. Endoscopic ultrasound-guided fine needle aspiration cytology of the pancreas: a morphological and multimodal approach to the diagnosis of solid and cystic mass lesions. Neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of prospective studies. The newly proposed Papanicolaou Society of Cytopathology terminology system for reporting pancreaticobiliary cytology is also discussed. This chapter outlines the various solid and cystic lesions of the pancreas emphasizing proper tissue triage and handling, cytological criteria, and a multimodal approach to diagnosis using clinical and imaging features, as well as ancillary pathological studies. For the pathologist, the differential diagnosis of a pancreatic mass will be focused by the patient’s history and imaging characteristics of the lesion (solid versus cystic). This method has many advantages over percutaneous FNA but introduces challenges with gastrointestinal contamination. Endoscopic ultrasound and fine-needle aspiration sampling (EUS-FNA) has become the favored method of biopsy over the past decade. ![]() Increasingly, neoadjuvant chemotherapy and/or radiation therapy has been used to treat resectable and borderline resectable cancers due to its ability to induce tumor regression, treat micro-metastases, and reduce the risk of positive margins and peritoneal implantation on resection. Preoperative biopsy of pancreatic masses and cysts is performed to provide a diagnosis and direct patient management, which ranges from conservative observation to surgery.
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